Different Pathogenicity of Duck Hepatitis A Virus 1 Between Pancreatitis-type and Classical Duckling
-
摘要: 为明确胰腺型鸭1型甲肝病毒 (DHAV-1) 和经典型DHAV-1对不同品种雏鸭的致病性, 以胰腺型DHAV-1和经典型DHAV-1分别感染7、14、21、28、35d番鸭、半番鸭、樱桃谷鸭和麻鸭, 结果表明番鸭对胰腺型DHAV-1最易感, 半番鸭和樱桃谷鸭次之, 麻鸭最不易感;而樱桃谷鸭对经典型DHAV-1最易感, 番鸭次之;感染胰腺型DHAV-1的番鸭、半番鸭胰腺出血、明显发黄, 肝脏未见出血。表明胰腺型鸭1型甲肝病毒、经典DHAV-1在易感宿主、组织嗜性和特征肉眼病变上均存在明显差异。Abstract: A duck hepatitis A virus 1 (DHAV-1) , designated pancreatitis-type DHAV-1, has been isolated from Muscovy ducklings with yellow or hemorrhagic pancreas.To elucidate different pathogenicity of DHAV-1infection between pancreatitis-type and classical ducklings, Muscovy duck, mallard duck, Cherry valley duck and Maya duck, raised for 7, 14, 21, 28and 35drespectively, were inoculated with pancreatitis-type and classical DHAV-1.The results showed that Muscovy duck was the most sensitive to pancreatitis-type DHAV-1, followed by mallard duck and Cherry valley duck, and the Maya duck was the lowest.However, Cherry valley duck was the most sensitive to classical DHAV-1, followed by Muscovy ducks.Hemorrhagic and yellow pancreas was detected in Muscovy duckling and mallard duckling infected with pancreatitis-type DHAV-1, but no hemorrhage in liver.The above indicated that there were obviously different pathogenicity between pancreatitis-type and classical DHAV-1in sensitive host, and gross lesions.
-
Key words:
- Duck Hepatitis A Virus type 1 /
- pancreatitis-type /
- pathogenicity
-
[1] SAIF Y M.禽病学[M].第12版.苏敬良, 高福, 索勋, 译.北京:中国农业出版社, 2005:431-443. [2] 郭玉璞, 蒋金书.鸭病[M].北京:北京农业大学出版社, 1988:30-31. [3] 苏敬良, 黄瑜, 贺荣莲, 等.新型鸭肝炎病毒的分离及初步鉴定[J].中国兽医科技, 2002, 32 (1) :15-16. [4] 黄安国, 蒋玉雯, 白安斌, 等.新型鸭肝炎病毒的分离与初步鉴定[J].广西畜牧兽医, 2003, 19 (5) :198-199. [5] TSENG C H, TSAI H J.Molecular characterization of a new serotype of duck hepatitis virus[J].Virus Res, 2007, 26 (1-2) :19-31. [6] KIM M C, KWON Y K, JOH S J, et al.Recent Korean isolates of duck hepatitis virus reveal the presence of a new geno-and serotype when compared to duck hepatitis virus type 1type strains[J].Arch Virol, 2007, 152 (11) :2059-2072. [7] GUERIN J L, ALBARIC O, NOUTARY V, et al.A duck hepatitis virus type I is agent of pancreatitis and encephalitis in Muscovy duckling.In:Proceedings of the 147th American Veterinary Medicine Association/50th American Association of Avian Pathologists Conference[C]//Washington DC, USA, 2007, Abs 4585. [8] 傅光华, 陈红梅, 黄瑜, 等.雏番鸭胰腺型鸭1型甲肝病毒分离鉴定及VP1基因分析[J].福建农业学报, 2012, 27 (9) :43-45. [9] 林曦.家畜病理学[M].中国农业出版社, 2000:170-172. [10] 殷震, 刘景华.动物病毒学[M].科学出版社, 1997:279-280. -
点击查看大图
计量
- 文章访问数: 176
- HTML全文浏览量: 33
- PDF下载量: 3
- 被引次数: 0
下载:
