中药方剂对自然感染PCV2断奶仔猪生长性能和猪瘟疫苗免疫应答的影响

林雪玲; 林伯全; 潘书磊; 赖宝色; 林秋敏; 练庆祥; 李建洪

doi:10.19303/j.issn.1008-0384.2013.10.005

中药方剂对自然感染PCV2断奶仔猪生长性能和猪瘟疫苗免疫应答的影响

doi: 10.19303/j.issn.1008-0384.2013.10.005

1. 福建农业职业技术学院动物科学系,福建福州,350119;
2. 福建三明恒祥农牧集团公司,福建三明,365000;
3. 福建莆田鸿达牧业有限公司,福建莆田,351100

基金项目:

福建省科技计划项目 (2012N3004)

详细信息

作者简介:
林雪玲 (1974-), 女, 硕士, 讲师, 主要从事临床兽医研究 (E-mail:linxueling0909@126.com)

中图分类号: S858.28
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- 被引次数: 0
出版历程
- 收稿日期: 2013-09-06
- 刊出日期: 2013-10-18

Effect of TCM on Growth and Immune-response to Hog Cholera Vaccine of Weaned Piglets Carrying Naturally Acquired Porcine Circovirus Type 2

1. Department of Animal Science,Fujian Agricultural Vocation-technical College;
2. Fujian Sanming Hengxiang,Agriculture and Animal Husbandry Group Company;
null. Fujian Putian Hongda Animal Husbandry Limited Liability Company

摘要

摘要: 探讨中药对自然感染猪圆环病毒2型 (PCV2) 仔猪生长性能和猪瘟疫苗免疫应答的影响, 结果显示:1%中药组、1.5%中药组、2.0%中药组的日增重分别比对照组提高30.40% (P<0.05) 、28.88% (P<0.05) 和31.06% (P<0.05) , 饲料转化率分别比对照组提高2.02%、7.25%和10.26%, 日采食量分别比对照组提高26.23%、14.75%和9.84%, 猪瘟抗体阻断率分别比对照组提高9.57%、18.27%和30.93% (P<0.05) , 猪瘟抗体阳性率均大于70%, 1.5%中药组、2.0%中药组的猪瘟抗体变异系数均小于40%。表明自拟中药方剂可较好地控制PCV2, 提高仔猪生长性能和增强猪瘟疫苗免疫应答, 且以2%中药组效果最好。
- 中药方剂 /
- 猪圆环病毒2型(PCV2) /
- 断奶仔猪生长性能 /
- 猪瘟疫苗免疫应答
Abstract: A traditional Chinese medicine (TCM) was formulated to study its effect on the growth and immuneresponse to the hog cholera vaccine of the piglets.The results showed that, as compared with Control, the daily weight gains of the piglets in Group A, B and C increased by 30.40% (P<0.05) , 28.88% (P<0.05) and 31.06% (P<0.05) , respectively;the feed conversion ratios increased by 2.02%, 7.25% and 10.26%, respectively;the daily feed intakes increased by 26.23%, 14.75% and 9.84%, respectively;and, the rates of blocking the classic swine fever antibody increased by 9.57%, 18.27% and 30.93% (P<0.05) , respectively.The rates of positive classic swine fever antibody in all three treatment groups were greater than 70%, and the variation coefficients of Group B and C were lower than 40%.It appeared that the TCM used had a measurable effect on PCV2infection, piglet growth, as well as the piglet's immune-response to the hog cholera vaccine.Insofar as TCM dosage is concerned, the best result was obtained on Group C that had a 2%addition on its feed.
- traditional Chinese medicine /
- PCV2 /
- weaned piglets /
- growth performance

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参考文献(18)

[1]	徐延川, 王衡, 张得玉, 等.广东省猪圆环病毒2型感染的血清学调查[J].动物医学进展, 2011, 32 (12) :79-83.
[2]	周秋平, 王家涛, 李发妮, 等.海南猪圆环病毒2型的流行病学调查[J].中国兽医杂志, 2008, 44 (1) :42-43.
[3]	汪招雄, 杨玉莹.湖北省猪场圆环病毒病和蓝耳病的血清学和流行病学调查[J].长江大学学报:自然科学版, 2010, 7 (4) :31-33.
[4]	卢寄军, 王祝荣, 张进.湖南省猪圆环病毒2型流行病学调查[J].中国动物检疫, 2012, 29 (2) :42-43.
[5]	胡慧, 王亚宾, 陈丽颖, 等.河南地区猪圆环病毒2型感染的血清流行病学调查[J].畜牧与兽医, 2010, 42 (10) :70-72.
[6]	金爱华, 卫秀余, 沈强.近两年我国猪圆环病毒II型流行病学调查[J].猪场保健, 2010, (3) :17-18.
[7]	SEGELES J, ROSELL C, DOMIGO M.Pachological findings associated with naturally acquired porcine circovirus type 2associated disease[J].Vet Microbiol, 2004, 98:137-149.
[8]	KRAKOWKA S, ELLIS J A.Viral wasting syndrome of swine:expenmenta1 reproduction of postweaning multisystemic wasting syndrome in gnotobiotic swine by coinfection with porcine circovirus 2 and porcine parvovirus[J].Vet Pathol, 2000, 37:254-263.
[9]	NIELSEN J, VINCENT I E, BOTNER A, et al.Associalion of lymphopenia with porcine circovirus type 2 induced postweaning multisystemic wasting syndrome (PMWS) [J].Vet Immunol Immunopathol, 2003, 92:97-111.
[10]	LADEKLAR-MIKKELSEN A S, NIELSEN J, STADEJEK T, et a1.Reproduction of postweaning multisystemic wasting syndrome (PMWS) in immunostimulated and nonimmunostimulated 3-week-old piglets experimentally infected with porcine circovirus type 2 (PCV2) [J].Vet Microbiol, 2002, 89:97-114.
[11]	杨小林, 陈关平.兽用抗菌抗病毒中草药的研究进展[J].长江大学学报:自然科学版, 2006, 3 (2) :151-154.
[12]	褚秀玲, 韦旭斌.抗病毒中草药研究进展[J].中兽医学杂志, 2006, (1) :33-37.
[13]	宋文双, 张勃, 韩开顺.浅谈猪的圆环病毒的防治[J].山东畜牧兽医, 2013, 34 (1) :83.
[14]	SEGALES J, ALONSO F, ROSELL C, et al.Changes in peripheral blood leukocyte populations in pigs with natural postweaning multisystemic wasting syndrome[J].Veterinary Immunology and Immunopathology, 2001, 81:37-44.
[15]	DARWICH L, SEGALES J, DOMINGO M, et al.Multisystemic wasting syndrome-affected pigs and age-matched unifected wasted and healthy pigs correlate with lesions and Porcine circovirus type 2load in lympoid tissues american society for Microbiology[J].Clinical and Diagnostic Laboratory Immunology, 2002, 9 (2) :236-242.
[16]	SANCHEZ Jr R E, MEERTS P, NAUWYNCK H J, et al.PCV2replication in lymph nodes of pigs inoculated in lategestation or postnatally:Virus quantification, immunophenotyping of target cells and relation to cli-nical and pathological outcome of infection[C]//Proceedings of the4th International Symposium on E-merging and Re-emerging Pig Diseases.Rome:Palazzo dei Congressi, 2003:162-163.
[17]	司兴奎, 顾万军, 张济培, 等.猪圆环病毒2型感染对高致病性猪繁殖与呼吸综合征疫苗免疫应答的影响[J].西北农业学报, 2011, 20 (5) :35-39.
[18]	司兴奎, 张济培, 陈建红, 等.猪圆环病毒2型感染对伪狂犬疫苗免疫应答的影响[J].中国预防兽医学报, 2010, 32 (1) :61-64.