Immunological Effect on Egg-laying Chickens by Combining Vaccinations Against Newcastle and Infectious Bursal Diseases

XING Dong; LIU Meng-xi; YUAN Xiao-qin; LI Chun-yan; CHEN Shi-yi; JIANG Xing-hua; ZHAO Hua-e; BAO Song-ying; WANG Quan-xi

doi:10.19303/j.issn.1008-0384.2017.09.002

Volume 32 Issue 9

Nov. 2017

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Article Navigation > Fujian Journal of Agricultural Sciences > 2017 > 32(9): 926-931

XING Dong, LIU Meng-xi, YUAN Xiao-qin, LI Chun-yan, CHEN Shi-yi, JIANG Xing-hua, ZHAO Hua-e, BAO Song-ying, WANG Quan-xi. Immunological Effect on Egg-laying Chickens by Combining Vaccinations Against Newcastle and Infectious Bursal Diseases[J]. Fujian Journal of Agricultural Sciences, 2017, 32(9): 926-931. doi: 10.19303/j.issn.1008-0384.2017.09.002

Citation:

XING Dong, LIU Meng-xi, YUAN Xiao-qin, LI Chun-yan, CHEN Shi-yi, JIANG Xing-hua, ZHAO Hua-e, BAO Song-ying, WANG Quan-xi. Immunological Effect on Egg-laying Chickens by Combining Vaccinations Against Newcastle and Infectious Bursal Diseases[J]. Fujian Journal of Agricultural Sciences, 2017, 32(9): 926-931. doi: 10.19303/j.issn.1008-0384.2017.09.002

Citation:

XING Dong, LIU Meng-xi, YUAN Xiao-qin, LI Chun-yan, CHEN Shi-yi, JIANG Xing-hua, ZHAO Hua-e, BAO Song-ying, WANG Quan-xi. Immunological Effect on Egg-laying Chickens by Combining Vaccinations Against Newcastle and Infectious Bursal Diseases[J]. Fujian Journal of Agricultural Sciences, 2017, 32(9): 926-931. doi: 10.19303/j.issn.1008-0384.2017.09.002

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Immunological Effect on Egg-laying Chickens by Combining Vaccinations Against Newcastle and Infectious Bursal Diseases

doi: 10.19303/j.issn.1008-0384.2017.09.002

1.
College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China
2.
Fuzhou Dabeinong Biotech Co. Ltd, Fuzhou, Fujian 350002, China

Received Date: 2017-02-17
Rev Recd Date: 2017-06-17
Publish Date: 2017-09-28

Abstract

Abstract

Immunological effect of combined inoculation of the inactivated vaccines for Newcastleand the infectious bursal diseases (ND-IBD) on egg-laying chickens was investigated. For the study, 360 one-day-old commercial chicks were randomly divided into 3 groups. The chicks in one group were immunized immediately with the two vaccines simultaneously, another when they were 7-day-old, and the third group injected with saline solution as control.Levels of ND-IBD antibodies in the serum ofthese chicks were determined, spleen biopsies for disease detection executed, and qPCR on mRNA expressions of CD4⁺, CD8⁺, IL-6 and IFN-β performed every 7 days during the period of 21 to 56 d. The results showed that all treated one-or 7-day-old birds had higher antibody levels than control, and could fence off IBD virus infection. The 7-day-old group showed greater immunity against the diseases, and significantly increased mRNA expressions on CD4⁺, CD8⁺, IL-6 and IFN-β over control. It was, therefore, concluded that, by combining vaccinations against ND-IBD on 7-day-old egg-laying chicks, a desirable immunological effect on the chickens could be achieved.
- newcastle disease,
- infectious bursal disease,
- inactivated vaccine,
- antibody detection

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References(23)

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