Abstract: Using Vitamin C solution as control in different concentrations, “brier grape wine”and“Gui-pu No1 wine”were studied with UV spectrophotometric assay on their scavenging activity to DPPH·, ·OH and reducing activity to potassium ferricyanide.The results showed that scavenging activity of two grape wines increased with the wine concentration.The scavenging activity to DPPH·in two wines were 2.75and 3.14time equivalent of it in Vc (2.0 mg·mL-1) , respectively, and to·OH were 6.98and 7.86time equivalent in 1.0 mg·mL-1, respectively.The scavenging speeds to free radicals were following the order in“Gui-pu No1wine”>“brier grape wine”>VC.There was no obvious difference between two wines in reducing activities to potassium ferricyanide but were higher in both wins than in Vc (0.5mg·mL-1) .