Abstract: Antigenic relationship of Muscovy duck parvovirus (MPV F strain) , Muscovy duck origin goose parvovirus (MDGPV PT strain) and Goose parvovirus (GPV GD strain) were determined by virus crossneutralization tests (NT) and latex agglutination inhibition test (LPAI) .The results showed that neutralization titer and LPAI titers of homologous antiserum were significantly higher than heterologous serum;R values of MPV compared with MDGPV and GPV were less than 0.1.R value between MDGPV and GPV was greater than 0.25.The results showed that MPV has low antigenic correlation with GPV and MDGPV, which indicated that antigenic variations are obviously existed between MPV and the other two, and showed that GPV and MDGPV belong to different subtypes of the same serotype.