Abstract: A traditional Chinese medicine (TCM) was formulated to study its effect on the growth and immuneresponse to the hog cholera vaccine of the piglets.The results showed that, as compared with Control, the daily weight gains of the piglets in Group A, B and C increased by 30.40% (P<0.05) , 28.88% (P<0.05) and 31.06% (P<0.05) , respectively;the feed conversion ratios increased by 2.02%, 7.25% and 10.26%, respectively;the daily feed intakes increased by 26.23%, 14.75% and 9.84%, respectively;and, the rates of blocking the classic swine fever antibody increased by 9.57%, 18.27% and 30.93% (P<0.05) , respectively.The rates of positive classic swine fever antibody in all three treatment groups were greater than 70%, and the variation coefficients of Group B and C were lower than 40%.It appeared that the TCM used had a measurable effect on PCV2infection, piglet growth, as well as the piglet's immune-response to the hog cholera vaccine.Insofar as TCM dosage is concerned, the best result was obtained on Group C that had a 2%addition on its feed.