Abstract: Thousand-grain weight(TGW)is one of the important indicators for rice yield determination.For the study,F1rice crossed from parents with significant difference on TGW and its F2by self-crossing the F1 were used. The TGW traits of P1,F1,P2and F2 were the basis for the evaluation.An optimal model was selected from the quantitative trait master+ multi-gene mixed inheritance models.The genetic prediction by the model indicated that the TGW of the crossed rice varieties followed a C-0mode,and the inherant rate of the main genes was 0.86%-0.97% while that of the multiple genes 68.06%-80.33%.The combined,overall rate for the genes to pass on from one generation to the next was 68.92%-81.30%.