Abstract: Microwave was applied for the extraction of polysaccharides from the stems of Clitocybe maxima.The parameters studied in the single-factor orthogonal experiment included material to liquid ratio,extraction time,and microwave power.The optimum conditions obtained were:the material to liquid ratio,1∶25;extract duration, 8min;and,microwave power,540W.Among them,microwave power exerted the greatest effect,while extraction time the least,on the polysaccharide extraction rate.Compared to the conventional hot water extraction,the new method had a 57.7% higher yield and 30.8% more polysaccharides.