Abstract: Breeding management for large population of 1500 pigs in large-scale piggery of microbial fermentation bed was studied on pig day age as the core, observing the weight, daily gain, feed, daily feed intake, F/G ratio (feed conversion ratio) and so on.Swine growth dynamic models were established, including (1) the model of pig weight (y) with age (x) :y = 0.7589 x-19.883 (R2= 0.9937) , (2) the power exponent relation model of pig weight increase (y) with age (x) :y = 1.0395 x0.5051 (R2= 0.8854) , (3) the model of pig average daily feed intake (y) with age (x) :y = 0.0235 x-0.3343 (R2=0.9917) , (4) the model of pig feed conversion ratio (y) with age (x) :y = 0.022 + 0.4278 x (R2=0.9885) , etc.The results were discriminated from the models as the theoretical value for pig growth under specific days of age.When the actual values of pig weight, pig gain, average daily feed intake, feed conversion ratio etc.were lower than the theoretical value, it must be found the reason to strengthen the management of swine.On observation of 1500-pigs group in large-scale piggery of microbial fermentation bed, it could be seen in the 60-65 days age that the pig average daily feed intake was lower than the theoretical value, showing that the pig had adaptive process to the microbial fermentation bed in early farming.By the 70-75 days of age the pig average daily feed intake was higher than the theoretical value, displaying that pig breeding had adapt to the microbial fermentation bed, especially in the 75 days of age the pig average daily feed intake increaced by 21%to reveal that the microbal fermentation bed was more conducive to the growth of pigs.The main diseases of pigs in microbial fermentation bed were dermatitis- pox macula, diarrhea and gastrointestinal diseases, cough-respiratory diseases, frozen pig-malnutrition, eye disease-conjunctivitis, trauma-turn feet, deadly infectious diseases was not found.The overall incidence of pig disease was low with less than 10%.The treatment for the disease was not difficult to strengthen the management of bedding, such as paying attention to feeding, ensuring water quality clean, many diseases could heal itself.