鸭传染性浆膜炎二价灭活疫苗制苗用菌株的筛选

Screening of Strains for the Bivalent Inactivated Vaccine Against Duck Infectious Serositis

摘要: 选取鸭疫里默氏菌血清1型和2型菌株各6株进行毒力比较, 结果发现不同菌株的毒力略有差异。选择毒力较强的鸭疫里默氏菌血清1型和2型菌株各3株制备灭活油乳剂疫苗, 免疫6日龄鸭后14d以同血清型菌株进行攻毒保护试验, RAf63株和RAf34株制备的疫苗免疫保护率最高, 是理想的制苗用菌株。

Abstract: The comparison tests of virulence of 12 Riemerella anatipestifer strains (serotype 1and 2, 6strains for each) were carried out.The virulence of different strains were different.6more virulent strains (3strains for each) were selected to prepare inactivated oil-emulsion vaccines.6days old ducklings were vaccinated for 14 days and then challenged with the same serotype strains.The immune protective rates of the vaccine prepared by strains RAf63 and RAf34were the highest.The strains RAf63 and RAf34were proved suitable for vaccine strains.