Abstract: To optimize the mushroom cultivation and minimize heavy metal migration from the medium to the fruiting body,Agrocybe cylindracea was used in this study.The migration patterns of lead,cadmium,arsenic and mercury from the spiked media to the mushrooms were monitored.The results showed that the content of the heavy metals in the mushroom fruiting bodies significantly correlated with that in the medium.Grown in the control medium,the fruiting bodies of the mushrooms contained these heavy metals within the limits for "green foods" as specified by the national standards.The metal contents in mushroom increased as the amount of the heavy metals were increased in the spiked media.It was also found that the heavy metal retention rates of A.cylindracea differed according to the order:mercury>cadmium>arsenic>lead.When mercury was added at a rate of 0.1mg/kg to the medium,up to 241.9percent accumulation of the metal in the harvested mushroom fruiting bodies was found.