Abstract: Murray cod,Maccullochella peelii peelii,is a freshwater fish newly introduced from Australia.Itoffers aconsiderable commercial potential because of its highly desirable nutritional value and palatability.However,Murray cod is vulnerable to a variety diseases.Numerous diseases caused by bacteria,fungi,and parasites are frequently found on the fish.Thus,thebreeding and cultivation conditions for the aquaculture must be maintained at anexceedingly hygienic level.Through careful analyses on the clinical symptoms,pathogens and the epidemiological characteristics of the susceptable diseases,applicable control measures are proposed.Hopefully,they would help prevent,reduce and/or alleviate the occurrence of the diseases facilitating the development of Murray cod aquaculture.