Abstract: “Duroc× Landrace×Yorkshire”commodity pigs around the age of 60 days were raised in the cement floor pigsty(control group)and microbial fermentation bed pigsty(experimental group),respectively,to feed for 120 d.At the end of the experiment,the experimental group and the control group were collected from 6pig blood tests.The results showed that,serum alkaline phosphatase activity in experimental group increased by 0.86%than that of control group(P>0.05),decreased 33.8% enzyme activities of alanine transfer(P<0.01),serum urea nitrogen content decreased by39.8%(P<0.01),the total cholesterol content increased by 9.4%(P<0.05),total bilirubin increased 36.4%(P>0.05),blood glucose reduced by 41.4%(P<0.01);IgA(g·L-1)were increased by 34.05%(P<0.01),IgG(g·L-1)was increased by 21.6%(P<0.01),IgM(g·L-1)increased by 17.3%(P<0.05);swine fever antibody titer than that of the control group increased more than 37%(P<0.05).The results showed that the large scale microbialfermentation bed feeding mode,can improve the pigs of sugar,protein and fat metabolism,reduce the porcine stress,improve the immunity of pigs,enhance the capacity of resistance.