Abstract: To select and optimize the flavonoid extraction technology on Salvia scapiformis Hance harvested from Mt.Leigong in Guizhou,various factor levels on an orthogonal experimentwere tested using reflux,ultrasound,and microwave in the process.The results showed that the microwave extraction method was the best among all,with a9.28% yield on total flavonoids.The optimal conditions for the processincluded a 2-minute application of microwave power at 400 W with asolid:liquid ratio of 1∶40and the use of 50%ethanol.And,the extraction procedureswere repeated to maximize the substance recovery.