• 中文核心期刊
  • CSCD来源期刊
  • 中国科技核心期刊
  • CA、CABI、ZR收录期刊

复方中草药和替米考星对仔猪免疫功能的影响

Effect of In-house Chinese Herbal Formulation and Tilmicosin on Immunity of Weaned Piglets

  • 摘要: 为探究复方中草药以及替米考星对仔猪免疫功能的影响效果,选用(25±2)日龄的三元杂交仔猪240头,随机分为8组,Ⅰ组(中药组)添加超微粉碎中草药进行饲喂(4、7、10kg·t-1);Ⅳ组(中西医组)添加超微粉碎中草药+20%替米考星进行饲喂(4kg·t-1+1kg·t-1、7kg·t-1+1kg·t-1、10kg·t-1+1kg·t-1);Ⅶ组添加20%替米考星进行饲喂(1kg·t-1);Ⅷ组为空白对照组。每组分别于免疫前1d和免疫后28d采血测猪繁殖与呼吸综合征抗体水平,血清中白蛋白、总蛋白、免疫球蛋白IgM、IgG以及补体C3含量。结果表明:免疫后28d检测,添加中、西医及组合处理平均抗体水平均高于对照组,其中0.4%中草药添加剂量+20%替米考星(IV组)抗体水平最高而且离散度较小,差异显著(P<0.05);免疫后28d检测各处理组血清总蛋白含量、白蛋白含量、免疫球蛋白IgG含量以及补体C3的含量与对照组比较显著升高(P<0.05);0.4%中草药添加剂量+20%替米考星(IV组)的免疫功能提升程度优于其他试验组和对照组。表明日粮添加中草药及替米考星均能提高仔猪免疫功能,中西医组合处理效果最好。

     

    Abstract: Effect of a custom-made Chinese herbal formulation(CHF)and tilmicosin on the immunity of weaned piglets were investigated.CHF consisting of Astragalus membranaceus,Codonopsis pilosula,Epimedium sagittatum,massa medicata fermentata,Atractylodes macrocephala,malt,Glycyrrhiza uralensis,Angelica sinensis and Crataegus pinnatifida was crushed and passed through a 500-mesh sieve for the experiment.The weaned 3-line crossbred piglets(age 25±2days)were randomly assigned to 8groups of 30 each.CHF was added to the basal diet for Group I,II,and III at levels of 4kg·t-1,7kg·t-1,and 10kg·t-1,respectively.Group IV,V,and VI were fed with CHF and 20%tilmicosin in the feed,i.e.4kg·t-1 CHF+1kg·t-1,7kg·t-1 CHF+1kg·t-1,and 10kg·t-1 CHF+1kg·t-1,respectively.Group VII was fed with a diet added 1kg·t-120%tilmicosin.As control,Group VIII was fed with the basal diet alone.One day before,and 28 ds after the PRRSV vaccination,blood samples from the piglets from each group were drawn to test for PRRSV Ab level,albumin,total protein,Ig M,Ig G,and complement C3 concentration.The results showed that 28 ds after the vaccination the average serum antibody levels in piglets of Group IV,V,and VI were higher than the control,especially Group IV,were the highest among all,with significant difference(P<0.05)and low data spreading.The concentrations of total protein,albumin,IgG,and complement C3 in all groups were greater than those of control,especially Group IV(P<0.05),were the highest(P<0.05).It appeared that the administration of CHF and tilmicosin enhanced the immunity and PRRSV Ab in the piglets,the best effects conld be received in treatment with both CHF and tilimicosin.

     

/

返回文章
返回