Abstract: Split-plot design with two experimental factors was used to study the effects of four cultivation modes and planting density on potato cultivar Zhongshu 3 in Southern China.Results showed that the yield and commodity quality of potato were significantly different with four cultivation modes or planting density.Comparatively, the highest potato yield was 47 925.0 kghm-2 obtained by the mode of straw mulching as sandwich plus density in 75 000 plants per hectare.Based on the yield, commodity rate and quality of the potato comprehensively, the best cultivation pattern were the mode of straw mulching as sandwich with planting density of 67 500 to 75 000 plants per hectare.