Abstract: The purpose of the experiment was to study the effect of the digestible energy and lysme on the performance and biochemical traits of growing-finishing pigs during constant high temperature period.Thtrty-two cross bred (Duroc×Long white×Large white)fatterting pigs.weighing an average of 44.1kg±1.8kg.were randomly assigned to four treatments.The level of the crude protem was 15.5%.The levels of energy were 13.23 MJ·kg1.13.73 MJ·kg1,14.93 MJ·kg-1.14.73 MJ·kg1,and the,levels of lysine were 0.676%.0.726%,0.764%.0.800% respectively.Results showed that:①High dietary energy and lysine level increased the body weight sigmficantly(P0.05)and decreased the Fecd/Gain ratio(P0.05).②With the increase of the dietary energy and lysine.the concentration of thyroxine(T3).total protein,globulin in the serum increased significantly(P0.05),and the concentration of Thyroxine(T4).glucose.albumin.increased insignificantly(P0.05).but the content of creatine kinase.triglyceride.Albumin/Globulin decreased significantly(P0.05).③With the increase of the dietary energy and lysine.serum K+ increased significantly(P0.05)and serum C1 decreased(P0.05),The energy and lysine had little effect on the serum Na+.④The energy and lysine increased the levels of blood antibody and lymphocyte ratio,and had a significant effect on Serum IgM(P0.05).and had a insignificant effect on the serum IgA.IgG and lvmphocvte ratio(P0.05).