Abstract: The effect of different density and fertilizer application on the photosynthesis, yield and quality of Minzinuo was studied by the population and the fertilizer character test. The result showed that the population leaf area developed reasonable while the planting density was 6.75?104·hm-2 and LAD, NAR and LAI were all the largest, dry matter accumulation was the maximum at the growing stage. The order of contribution to yield was N >K>P. N fertilizer had the largest effect on the weight, protein content and starch content of maize. The Optimal of N, P, K was N 187.5 kg·hm-2, P112.5 kg·hm-2 and K 180 kg·hm-2.