Molecular Epidemiology of Enzootic Nasal Tumor Virus on Goats in Fujian

The pathogen that caused a disease characterized by thin nasal discharge on goats in Fujian during 2014-2017 was investigated.An epidemiological survey of the disease was conducted with tumor tissue biopsy, specific PCR diagnosis, and nucleic acid sequence analysis. It was found that the disease had basically the sam eepidemiology, clinical symptoms, pathology, and histopathology as the similar cases reported domestically and abroad. RT-PCR identified the pathogen to be ENTV-2. Among the various isolated viruses, 7 were in the same phylogenetic tree branch as ENTV-2 CHN2, and one in the branch as ENTV-SC and ENTV-Shaanxi, which were all isolated in China.The results confirmed ENTV-2 to be the culprit of the disease in goats found in Fujian Province. Hopefully, with the information, a prevention measure and/or cure for the disease could be developed in the near future.