• 中文核心期刊
  • CSCD来源期刊
  • 中国科技核心期刊
  • CA、CABI、ZR收录期刊
Volume 26 Issue 6
Feb.  2012
Turn off MathJax
Article Contents
Abstract
References
Related Articles
LIAO Bi-chai. Pharmacokinetics and Residues of Norfloxacin in Hybrid Tilapia[J]. Fujian Journal of Agricultural Sciences, 2011, 26(6): 930-934.
Citation: LIAO Bi-chai. Pharmacokinetics and Residues of Norfloxacin in Hybrid Tilapia[J]. Fujian Journal of Agricultural Sciences, 2011, 26(6): 930-934.
shu

Pharmacokinetics and Residues of Norfloxacin in Hybrid Tilapia

  • 1.

    The Freshwater Fisheries Research Institute of Fujian Province,Fuzhou, Fujian 350002, China;

  • 2.

    Fujian Fishery Technical Extension Center,Fuzhou, Fujian 350003, China

More Information
  • Received Date: January 13, 2011
  • Revised Date: June 02, 2011
    Graphical Abstract
    • Abstract
  • In order to study the metabolism and elimination of norfloxacin (NFX) in hybrid tilapias (Oreochromis aureusO.niloticus), single oral administration at dose of 20 mgkg-1 had been investigated in healthy tilapia at (252)℃.The result demonstrated: Plasma concentration-time datas of NFX were best fitted using a two-compartmental open model.Absorption, distribution and elimination half-life were 1.30,1.97 and 26.36 hours, respectively.The maximal plasma concentration was 0.546 gmL-1, peaking at 2.715 hour.Area under the plasma drug concentration-time curve was 14.491 ghmL-1.As an edible tissue, muscle was selected as target tissue in this experiment.The maximum residue limit (MRL) is 10 gkg-1 in muscle, the withdrawal time should not be less than 55 days under this experiment condition.
    • FullText(HTML)
    • References (6)
  • 竺心影.药理学:第3版[M].北京:人民卫生出版社,1995:310.
    李继昌,鲁成武,符春燕,等.氟喹诺酮类药物在禽病防治上的应用[J].黑龙江畜牧兽医,1998,10:27.
    郭海燕,陈元坤,朱林,等.诺氟沙星在草鱼体内的组织分布和药物动力学规律[J].水产科学,2009,28(1):28-31.
    BJORKLUMD H V,BYLUND G. Temperature related absorption and excretion of oxytetracycline in rainbow trout[J]. Aquaculture,1990,84:363-372.
    • Related Articles

  • Related Articles

    [1]LU Yan-ping, YANG Guang, WU Jia-lun. Effects of Processing and Temperature on Imidacloprid Residues in Chrysanthemum morifolium[J]. Fujian Journal of Agricultural Sciences, 2017, 32(11): 1251-1256. DOI: 10.19303/j.issn.1008-0384.2017.011.016
    [2]PAN Wei, LIU Wen-jing. Pharmacokinetics and Residues of Mequindox in American Eel[J]. Fujian Journal of Agricultural Sciences, 2016, 31(10): 1028-1033. DOI: 10.19303/j.issn.1008-0384.2016.10.005
    [3]CENG Ming-sen, LIU Feng-jing, HUANG Huo-shui, WANG Ding-feng, RONG Jie-feng, WU Guang-yuan. Residue and Safety of Tolfenpyrad Used in Tea Plantations[J]. Fujian Journal of Agricultural Sciences, 2014, 29(8): 774-778. DOI: 10.19303/j.issn.1008-0384.2014.08.012
    [4]WANG Si-wei, LIU Yan-ping, SUN Hai-bin. Dissipation and Terminal Residue of Azoxystrobin in Lychee Under Field Conditions[J]. Fujian Journal of Agricultural Sciences, 2014, 29(2): 168-171. DOI: 10.19303/j.issn.1008-0384.2014.02.015
    [5]HU Gui-ping, ZHAO Yan, LIU Bo, YOU Min-sheng. Investigation of Organic Chlorine Residues in the Soil of Tea Garden[J]. Fujian Journal of Agricultural Sciences, 2013, 28(1): 60-65. DOI: 10.19303/j.issn.1008-0384.2013.01.015
    [6]WU Guang-yuan, ZENG Ming-sen, WANG Qing-sen, XIA Hui-long. Propargite Residue in Teas[J]. Fujian Journal of Agricultural Sciences, 2012, 27(4): 350-354.
    [7]PAN Wei, CHEN You-sheng, HUANG Xing, LUO Qin, RAO Qiu-hua, LAN Jian-you, CHEN Ren-bi. Drug residues in fish raised on feed containing trace enrofloxacin and furazolidone[J]. Fujian Journal of Agricultural Sciences, 2010, 25(5): 554-557.
    [8]ZENG Qiang, LIN Yong, HUANG Qiong-hui, ZOU Hua-jiao, Lü Zhou-ming, LIU Xin. JS118 degradation and final residue in cauliflower plants and soil[J]. Fujian Journal of Agricultural Sciences, 2007, 22(1): 19-22.
    [9]Chen Yian, Lin yincuen, Wang Caingsong, Liu Bo, Yu Deyi, Song Xiaochuan. Study on Butachlor Residues in Vegetables and Environment[J]. Fujian Journal of Agricultural Sciences, 1995, 10(3): 47-49.
    [10]Chen Yian, Chai Qinhua, Wang Qinsong, Li yinchung. RESEARCH ON METHOD OF ANALYESE OF RESIDUES CONTENT OF BUTACHLOR IN BRASSICA CHINESIS LINN. AND IPOMOEAREPTANS (L.) POIR[J]. Fujian Journal of Agricultural Sciences, 1990, 5(2): 64-66.

Catalog

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (3017) PDF downloads (538) Cited by()
    Related

    Copyright © 2018 Fujian Journal of Agricultural Sciences, All Rights Reserved. 闽ICP备19004781号-1 网安备：35010046024-23001

    Address: 247 Wusi Road, Fuzhou City China Pos: 350003 Tel: 0591-87869455 E-mail: fjnyxb@163.com

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return