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CHEN Shi-long, XIAO Shi-feng, CHENG Xiao-xia, LIN Feng-qing, WANG Shao, WANG Jin-xiang, ZHU Xiao-li, CHEN Shao-ying. Efficacy Evaluation of a Concentrated Inactivated Vaccine against Novel Duckling Reovirus Infection[J]. Fujian Journal of Agricultural Sciences, 2017, 32(11): 1189-1192. DOI: 10.19303/j.issn.1008-0384.2017.011.004
Citation: CHEN Shi-long, XIAO Shi-feng, CHENG Xiao-xia, LIN Feng-qing, WANG Shao, WANG Jin-xiang, ZHU Xiao-li, CHEN Shao-ying. Efficacy Evaluation of a Concentrated Inactivated Vaccine against Novel Duckling Reovirus Infection[J]. Fujian Journal of Agricultural Sciences, 2017, 32(11): 1189-1192. DOI: 10.19303/j.issn.1008-0384.2017.011.004

Efficacy Evaluation of a Concentrated Inactivated Vaccine against Novel Duckling Reovirus Infection

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  • Received Date: July 14, 2017
  • Revised Date: September 19, 2017
  • In this paper, an experimental concentrated inactivated vaccine and a conventional inactivated vaccine against Novel Duckling Reovirus (NDRV) infection were prepared. After one single-dose immunization in adult Cherry Valley ducks, the serum samples collected in a period of 13 weeks were tested for antibodies by serum neutralisation (SN) method. The protective effects against NDRV infection were observed in 3-day-old Cherry Valley ducklings and mule duckling after a single-dose immunization. The serological results showed that concentrated inactivated vaccine was much more immunogenic than the conventional inactivated vaccine, with a much higher SN antibody titers at all test time points. The concentrated inactivated vaccine was highly protective against NDRV challenge at 7-day post-vaccination with a 100% protective efficacy, as compared to 40%-60% protective efficacy for conventional inactivated vaccine. Taken together, this experimental concentrated inactivated vaccine exhibited immune efficiency much superior to conventional inactivated vaccine and might be a useful vaccine against NDRV infection.
  • [1]
    陈少莺, 陈仕龙, 林锋强, 等.一种新的鸭病(暂名鸭出血性坏死性肝炎)病原学研究初报[J].中国农学通报, 2009, 25(16):28-31. http://www.cnki.com.cn/Article/CJFDTOTAL-ZJNB201406010.htm
    [2]
    陈仕龙, 陈少莺, 程晓霞, 等.新型鸭呼肠孤病毒分离株的致病性研究[J].西北农林科技大学学报:自然科学版, 2010, 38(4):14-18. http://d.old.wanfangdata.com.cn/Conference/7295811
    [3]
    陈少莺, 陈仕龙, 林锋强, 等.新型鸭呼肠孤病毒的分离与鉴定[J].病毒学报, 2012, (3):224-230. http://www.cnki.com.cn/Article/CJFDTOTAL-BDXB201203008.htm
    [4]
    陈仕龙, 李兆龙, 林锋强, 等.新型鸭呼肠孤病毒病灭活疫苗的制备及免疫原性分析[J].福建农业学报, 2012, 27(5):461-464. http://www.fjnyxb.cn/CN/abstract/abstract1905.shtml
    [5]
    程晓霞, 陈少莺, 林锋强, 等.番鸭呼肠孤病毒弱毒疫苗在番鸭体内中和抗体消长规律的研究[J].福建农业学报, 2014, 29(1):5-7. http://www.fjnyxb.cn/CN/abstract/abstract2338.shtml
    [6]
    殷震, 刘景华.动物病毒学:第2版[M].北京:科学出版社, 1997:336-339.
    [7]
    刘源远.灭活疫苗中抗原浓缩对有效预防家禽主要传染病的重要性[J].养禽与禽病防治, 2004, (10):37-38. http://www.cqvip.com/qk/92765X/200410
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